Soha is a niche healer for aggressive team comps, usually consisting of a Warrior/Assassin to increase their overall survivability and to make full use of Sohas kit.
Since she is lacking any sort of damage dealing potential aisde from basic attacks you are free to build her as a dedicated tank which is actually quite usefull in some situations. The chosen setup is serving only one purpose, capping evasion and resistance while stacking as many base defensive stats as possible. If you already hit the cap without one of the dedicated rune sets you can replace it with either more base stats or another set to hit the cap for your missing stat.
You do need some accuracy if you want to make use of her buff removal, it can be resisted and unlike other debuffs you can go over the cap of 85% (there is a 15% minimum resist for most debuffs no matter if you have 85 or 100%). Though it would be unneccesary to go for the full 100% for most encounters. You are trying for 120k HP, 4k Def and Evasion/Res cap but this is already taking books into consideration. Acc should also be pushed as high as toleratable for your current rune setup.
The strenght in this setup comes into play as soon as either an assassin or summoner targets her, she is among the tankiest units on the field so killing her will take great effort. It is also allowing her to ignore common A.I. whoopsies such as walking into the moshpit that is the middle of the arena.
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